Combinatorial Extension with Circular Permutations

Concanavalin A (yellow & orange) aligned with Pea Leptin (blue and
cyan)

Combinatorial Extension with Circular Permutations (CE-CP) is a structural comparison algorithm provided by BioJava. It provides the ability to compare protein structures related by a circular permutation. In circularly permutated proteins, the N-terminal part of one protein is related to the C-terminal part of the other, and vice versa. For more information on circular permutations, see the Wikipedia or Molecule of the Month articles.

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